Acute soft head syndrome in patient with sickle cell disease.
Acute soft head syndrome
We present a 16-year-old male patient, known to have sickle cell anemia (Hb-SS) diagnosed at the age of 6 months and maintained on treatment with hydroxyurea. He presented to our emergency department with few hours onset of low-grade fever and headache. The headache was intractable and all over his head. He described it as pulsating and non-tolerable and could not be alleviated by analgesic.
Patient was admitted for treatment. Images were performed, non-enhanced MRI of the brain showed diffuse subgaleal collections with a predominant high T2 signal, iso T1 signal along with areas of high FLAIR and restricted diffusion signal in the frontal, bilateral parietal and occipital calvarium and small foci of susceptibility on T2* suggestive of punctate blood product
Acute soft head syndrome is a diagnosis of exclusion and should be always considered in a sickle cell patient that presents with headache and swelling.